بررسی اثر مدل‌های رفتاری مختلف ماده بر شاخص‌های انتشار امواج فراصوتی در استخوان به‌منظور تشخیص پوکی‌استخوان

پذیرفته شده برای ارائه شفاهی ، صفحه 1-11 (11) اصل مقاله (1017.32 K)

کد مقاله : 1141-ISAV2022 (R4)

نویسندگان

¹محمد حسین گندم‌کار؛ ²محمدحسین سورگی ؛ ¹مهدی مهدیزاده کفاش

¹دانشگاه شهید بهشتی

²Faculty of Mechanical and Energy Engineering. Shahid Beheshti University

چکیده

پوکی‌استخوان که از شایع‌ترین بیماری‌های استخوانی هست مستقیماً سلامت استخوان را مورد هدف قرار داده و سبب تخریب تدریجی بافت استخوانی و درنهایت بروز شکستگی می‌شود. باوجوداینکه سابقه استفاده از رویکرد فراصوت در کاربردهای بالینی در دهه‌های اخیر به‌شدت موردتوجه واقع شده است بااین‌حال این زمینه استخوان‌پزشکی به کمک فراصوت هنوز به کمال خود نرسیده است و هنوز از پتانسیل بالقوه به جهت تشخیص عارضه پیشگیری از پوکی‌استخوان برخوردار است. در این مقاله با انتشار عبور دادن موج فراصوت درون مقطع دوبعدی از استخوان فمور به کمک نرم‌افزار آباکوس سعی بر آن است تا با استخراج شاخص سرعت بتوان برهم‌کنش موج در مقابله با پوکی را موردبررسی قرار داد. به این منظور برای مقطع فمور چهار حالت، شامل یک کیفیت سالم و سه حالت پوک، در نظر گرفته شده است. مدل‌‌های پوک با کاهش مدول یانگ و چگالی استخوان اسفنجی یا ترابکولار حاصل گشته است. به‌منظور بررسی سرعت موج از شبیه‌سازی انتشار موج در فرم آزمون فراصوتی ارسال - دریافت استفاده شده است. نتایج شبیه‌سازی نشان می‌دهد که با پیشرفت پوکی، سرعت کاهش یافته و زمان به ثبت رسیدن موج در حسگر گیرنده با تأخیر همراه است.

کلیدواژه ها

پوکی‌استخوان؛ فراصوت مقداری؛ انتشار امواج فراصوت؛ آباکوس

Title

Study the effect of different behavioral models on principles of ultrasound propagation in bone toward to diagnosis of osteoporosis

Authors

Mohammad Hosein Gandomkar, Mohammad Hosein Soorge, Mehdi Mehdizadeh kafash

Abstract

Osteoporosis, which is one of the most widespread bone diseases, directly affects bone health and causes the gradual destroying of bone tissue and eventually causes fragility. Even if the history of utilizing ultrasound in clinical applications has received high praise in recent years, the field of orthopaedics has not yet attained its ideal and still lacks the ability to recognize the the issue of osteoporosis prevention. In this article, it is attempted to explore the interaction of the wave in dealing with osteoporosis by identifying the speed index using the transmission of ultrasound waves in the two-dimensional section of the femur bone with the assistance of Abaqus software. For this purpose, four models, including one of healthy quality and three of osteoporotic condition, have been taken into consideration for the femur section. osteoporotic models are obtained by reducing Young's modulus and density of cancellous or bone trabecular. In order to evaluate the speed of ultrasound, simulation of wave propagation has been used in the form of ultrasonic through-transmission test. Results show that with the progress of osteoporosis, the speed of the ultrasound is reduced and a delay is related with the time it takes for the wave to be received by the receiver sensor.

Keywords

Osteoporosis, Quantitative ultrasound, wave propagation, ABAQUS

مراجع

<div class="page" title="Page 9"> <div class="layoutArea"> <div class="column"><ol dir="ltr"> <li> J. Kanis et al., "European guidance for the diagnosis and management of osteoporosis in postmenopausal women," Osteoporosis international, vol. 19, no. 4, pp. 399-428, 2008. </li> <li> C. Njeh, C. Boivin, and C. Langton, "The role of ultrasound in the assessment of osteoporosis: a review," Osteoporosis international, vol. 7, no. 1, pp. 7-22, 1997. </li> <li> ترکمن، طناز و سورگی، محمدحسین،1397،شبیه سازی تشخص پوکی استخوان با استفاده از امواج فراصوتی،پنجمین . 867367/https://civilica.com/docکنفرانس بینالمللی آزمونهای غیرمخرب ایران،تهران، </li> <li> C. Langton, S. Palmer, and R. Porter, "The measurement of broadband ultrasonic attenuation in cancellous bone," Engineering in medicine, vol. 13, no. 2, pp. 89-91, 1984 </li> <li> E. Glushkov, N. Glushkova, O. Ermolenko, and A. Tatarinov, "Analysis of the ultrasonic guided wave sensitivity to the bone structure for osteoporosis diagnostics," in International Conference on Physics and Mechanics of New Materials and Their Applications, 2021: Springer, pp. 409-424  </li> <li> B. Vafaeian, Y. Wu, M. R. Doschak, M. El-Rich, T. El-Bialy, and S. Adeeb, "Finite Element Simulation of Ultrasound Propagation in Trabecular Bone," in ASME International Mechanical Engineering Congress and Exposition, 2013, vol. 56437: American Society of Mechanical Engineers, p. V014T15A038 . </li> <li> C. Sandino, D. D. McErlain, J. Schipilow, and S. K. Boyd, "Mechanical stimuli of trabecular bone in osteoporosis: A numerical simulation by finite element analysis of microarchitecture," Journal of the mechanical behavior of biomedical materials, vol. 66, pp. 19-27, 2017. </li> <li> C. Sandino, D. D. McErlain, J. Schipilow, and S. K. Boyd, "The poro-viscoelastic properties of trabecular bone: a micro computed tomography-based finite element study," Journal of the mechanical behavior of biomedical materials, vol. 44, pp. 1-9, 2015. </li> <li> X. Ojanen, "Relationships of microstructure and composition with material and macro level viscoelastic properties of trabecular bone," Itä-Suomen yliopisto, 2017 . </li> <li> J. Chen et al., "Measurement of guided mode wavenumbers in soft tissue–bone mimicking phantoms using ultrasonic axial transmission," Physics in Medicine & Biology, vol. 57, no. 10, p. 3025, 2012 </li> <li> T. Falardeau and P. Belanger, "Ultrasound tomography in bone mimicking phantoms: Simulations and experiments," The Journal of the Acoustical Society of America ,vol. 144, no. 5, pp. 2937-2946, 2018. </li> <li> V. C. Protopappas, I. C. Kourtis, L. C. Kourtis, K. N. Malizos, C. V. Massalas, and D. I. Fotiadis, "Three-dimensional finite element modeling of guided ultrasound wave propagation in intact and healing long bones," The Journal of the Acoustical Society of America, vol. 121, no. 6, pp. 3907-3921, 2007 </li> <li> W. Lin, Y.-X. Qin, and C. Rubin, "Ultrasonic wave propagation in trabecular bone predicted by the stratified model," Annals of biomedical engineering, vol. 2 ,9no. 9, pp. 781-790, 2001. </li> <li> A. Oral, S. Esmaeilzadeh, A. Yalıman, D. Sindel, P. K. Köseoğlu, and T. Aydın, "The ability of calcaneal and multisite quantitative ultrasound variables in the identification of osteoporosis in women and men," Turkish journal of physical medicine and rehabilitation,vol. 65, no. 3, p. 203, 2019. </li> <li> B. Vafaeian, M. El-Rich, T. El-Bialy, and S. Adeeb, "The finite element method for micro- scale modeling of ultrasound propagation in cancellous bone," Ultrasonics, vol. 54, no. 6, pp.2014 ,1663-1676 </li> <li> N. Rucci, "Molecular biology of bone remodelling," Clinical cases in mineral and bone metabolism, vol. 5, no. 1, p. 49, 2008 </li> <li> C. J. Boushey, A. M. Coulston, C. L. Rock, and E. Monsen, Nutrition in the Prevention and Treatment of Disease. Elsevier, 2001 </li> <li> C. C. Glüer and I. Q. U. C. Group, "Quantitative ultrasound techniques for the assessment of osteoporosis: expert agreement on current status," Journal of Bone and Mineral Research, vol. 12, no. 8, pp. 1280-1288, 1.997 </li> <li> M. Wesley P. Fairfield, ECNU. "Osteoporosis: When bones break easily."https://thewestendnews.com/osteoporosis-when-bones-break-easily/ (accessed. </li> <li> K. Someya et al., "Age-and sex-related characteristics in cortical thickness of femoral diaphysis for young and elderly subjects," Journal of bone and mineral metabolism, vol. 38 no. 4, pp. 533-543, 2020. </li> <li> W. Du, J. Zhang, and J. Hu, "A method to determine cortical bone thickness of human femur and tibia using clinical CT scans," in 2018 IRCOBI conference proceedings, Athens (Greece), 2018, pp. 403-412  </li> <li> I. C. Levine, L. E. Minty, and A. C. Laing, "Factors that influence soft tissue thickness over the greater trochanter: application to understanding hip fractures," Clinical anatomy, vol ,28 . no. 2, pp. 253-261, 2015. </li> <li> J. Lotz, E. Cheal, and W. Hayes, "Stress distributions within the proximal femur during gait and falls: implications for osteoporotic fracture," Osteoporosis International, vol. 5, no. 4, pp. .1995 ,252-261 </li> <li> B. Li and R. M. Aspden, "Composition and mechanical properties of cancellous bone from the femoral head of patients with osteoporosis or osteoarthritis," Journal of bone and mineral research, vol. 12, no. 4, pp. 641-651, 1997. </li> <li> M. H. Soorgee, C. J. Lissenden, J. L. Rose, and A. Yousefi-Koma, "Defect sensitivity of piezoelectric strip transducers based on planar Lamb waves," Journal of Intelligent Material Systems and Structures, vol. 25, no. 4, pp. 472-483, 2014 </li> </ol></div> </div> </div>